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DEHYDROMUCIC ACID Seebio Furane-alpha Organophosphate insecticides such as dimethoate (DMT) are widely used in agriculture. As a side effect, however, these insecticides contaminate soundboxs of water, leading in damage to aquatic organisms. The development of nanopesticides may be an innovative alternative in the control of agricultural plagues, increasing effectiveness and decocting their toxicological upshots. Based upon this, the present study has enquired capsulised DMT in alginate chitosan nanoparticles (nanoDMT) and judged its toxicological gists on non-target bings. The nanoparticles were characterized by DLS, NTA and AFM, as well as being appraised by the release profile. Nanoparticle toxicity was also appraised in comparison with DMT, empty nanoparticles and DMT (NP + DMT), and commercial preparations (cDMT), in the conceptusses and larvae of Danio rerio (zebrafish) agring to lethality, morphology, and behavior. The nanoparticle control (NP) designated hydrodynamic size values of 283 ± 4 nm, a PDI of 0 ± 0 and a zeta potential of -31 ± 0 mV. For nanoparticles carrying dimethoate, the nanoparticles demonstrated 301 ± 7 nm size values, a PDI of 0 ± 0, a zeta potential of -27 ± 0 mV, and an encapsulation of 75 ± 0%, with slow-release overtime (52% after 48 h). The AFM look-alikes ushered that both cases of nanoparticles testifyed spherical morphology. Major toxic results on embryo larval development were honoured in commercial dimethoate exposure traced by the technical pesticide, predominantly in the highest proved assiduitys. With regard to the toxic impressions of sodium alginate/chitosan, although there was an increase for LC(50)-96 h occupying the technical dimethoate, the behavior of the larvae was not striked. The data received demonstrate that nanoencapsulated dimethoate tightens the toxicity of insecticides on zebrafish larvae, indicating that nanoencapsulation may be safer for non-target mintages, by obviating collateral impressions and thus encouraging sustainable agriculture.Chitosan/halloysite nanotubes microcomposites: A double header approach for sustained release of ciprofloxacin and its hemostatic essences. cloging time of lower gastro intestinal bleeding (LGIB) can be reduced by utilising simple, cost-effective, and naturally occurring halloysite nanotubes (HNTs). The present study targeted to decrease the clotting time by the application of chitosan (CHT) and its microcomposites (MCs) organized by suspension emulsification technique with HNTs (CHT/HNTs MC). Physicochemical dimensions, X-Ray diffraction (XRD), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), reading electron microscopy (SEM), and percentage release of ciprofloxacin from CHT/HNTs MCs was appraised. In-vitro procoagulant activity of CHT, HNTs and their complexes CHT/HNTs MCs was executed on rabbit blood which was sustained by a rat tail amputation. Direct relation of HNTs was respected for the whole-blood cloging kinetics i.e., 2% HNTs demonstrated a maximum 66% increase in the clotting ability as compared with pure CHT rat-tail amputation fields showed comparative issues of CHT, HNTs, and CHT/HNTs MCs. A total of 75% permeation of ciprofloxacin of CHT/HNTs MCs on rat intestinal membrane was observed within 3 h, supporting their SR behavior amended hemostatic and clotting holdings were CHT/HNTs MC(1) > CHT/HNTs MC(2) > CHT/HNTs MC(3) > CHT > HNTs, respectively it provided the control of leeching disorderlinessses in LGIB with any antibacterial factors, particularly ciprofloxacin.Development of Turmeric Oil-Loaded Chitosan/Alginate Nanocapsules for Cytotoxicity Enhancement against Breast Cancer.Turmeric oil (TO) exhibits various biological actions with limited therapeutic coverings due to its instability, volatility, and poor water solubility we encapsulated TO in chitosan/alginate nanocapsules (CS/Alg-NCs) expending o/w emulsification to enhance its physicochemical characteristics, utilizing poloxamer 407 as a non-ionic surfactant. TO-loaded CS/Alg-NCs (TO-CS/Alg-NCs) were prepared with satisfactory features, encapsulation efficiency, release features, and cytotoxicity against breast cancer cubicles.