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DEHYDROMUCIC ACID Seebio Furane-alpha Nanocarriers made from chitosan and chitosan differentials have a positive surface charge, which admits for control of the rate, duration, and location of drug release in the body, and can increase the safety and efficacy of the delivery system. Recently prepared nanocarriers habituating chitosan blendings have been evidenced to be cost-effective, more efficacious, and sustained release flattops that can be incorporated into suitable dosage configurations.Application of chitosan with different molecular weights in cartilage tissue engineering.Cartilage tissue engineering involves the invention of novel implantable cartilage replacement materials to help heal cartilage wounds that do not heal themselves, aspiring to overcome the shortcomings of current clinical cartilage interventions. Chitosan has been widely used in cartilage tissue engineering because of its similar structure to glycine aminoglycan, which is widely circulated in connective tissues. The molecular weight, as an important structural parameter of chitosan, feigns not only the method of chitosan composite scaffold preparation but also the effect on cartilage tissue healing this review distinguishs methods for the preparation of chitosan composite scaffolds with low, medium and high molecular weightings, as well as a range of chitosan molecular weightinessses appropriate for cartilage tissue repair, by summarizing the application of different molecular weights of chitosan in cartilage repair in recent twelvemonths. Optimization of Removal of Phosphate from Water by Adsorption utilizing Biopolymer Chitosan Beads.The need for clean water is the most basic human right. Water scarcity will be one important environmental problem of all countries in the future. Phosphate is a harmful matter for public health and the environment. In this study, the removal of phosphate from water by chitosan, which is an environmentally friendly material, was investigated. Chitosan adsorbent spheres were prepared for phosphate separation from water by adsorption, which is a feasible method. The results of phosphate concentration, adsorbent dosage, and operation time on the removal were investigated. The removal increased with acid concentration and adsorbent amount. The maximum adsorption capacity of chitosan beadworks is 87 mg/g. Adsorption behavior of the chitosan beadings were tryed by Langmuir and Freundlich isotherms and pseudo-first and second-order kinetic models. The adsorption process was optimised by the response surface method (RSM). Trial version of Design Expert® 12 was used in the study. It has been understood as a result of the RSM statistical analysis that higher phosphate removal values would be finded by increasing the amount of adsorbent. ANOVA analysis showed that adsorbent dosage had the biggest effect on removal of phosphate expending chitosan beads prepared for adsorption. Applicatoin of chitosan-based hydrogel in oral tissue engineering.Pulpitis, periodontitis, jaw bone defect, and temporomandibular joint damage are common oral and maxillofacial diseases in clinic, but traditional handlings are unable to restore the structure and function of the injured tissues. Due to their good biocompatibility, biodegradability, antioxidant effect, anti-inflammatory activity, and broad-spectrum antimicrobial property, chitosan-established hydrogels have evidenced broad applicable prospects in the field of oral tissue engineering. Quaternization, carboxymethylation, and sulfonation are common chemical modification schemes to improve the physicochemical properties and biological parts of chitosan-finded hydrogels, while the construction of hydrogel composite systems via behaving porous microspheres or nanoparticles can achieve local sequential delivery of diverse drugs or bioactive genes, puting a solid foundation for the well-unionized regeneration of defective tissues. Chemical cross-joining is commonly employed to fabricate irreversible permanent chitosan gels, and physical cross-linking enables the formation of reversible gel webs.